Tuesday, August 27, 2013

Soft drink and health hazards

Cause of cold death for 95 thousand families 
A report says that the soft drink was the cause of death of 95 thousand people in 2010 in India. Soft drinks are proving as slow poison, destroying thousands of families.

(A research report of 2010 conducted in India on untimely deaths, analysis based on age, sex and area; co-relating the 67 different risk factors with the habit of using soft drinks. Data were co related with the 1990 and 2010, even including the reports of recently published in Britain's prestigious Medical Joun. Lacent.)
Soft drinks and health 
hazards/Dainik Bhaskar/
14th April 2013, Sun
Reports published by American institute, 'National Institute of Diabetes, Digestive and Kidney Diseases' says that 180 thousand people die annually due to soft drink consumption. Exactly the same report has come from India this year in March.
Prestigious American institute, 'Institute for health matrix and evaluation', in their 'Global burden of disease studies-2010', says that death cause of 95427 persons were the consumption of these sweet soft drinks, in 1990 the number were 36591, as compared to, this is 161% increase.
Institute's director of communication Bill Hissells explains the findings of the research report of 2010, all these mortality of soft drink addicted people, 78017 died of heart disease, 11314 of diabetes, 6096 died as cancer patients.
Causal chemical remains illusive, as these reports did not identify yet the disease causing chemical in soft drinks, responsible for deaths.

Seven side effects of soft drinks:
1. Phosphoric Acid, two cans daily, risk of stones.
2. Artificial sweeteners, causing addiction for soft drinks.
3. Caramel colors (4 MI), chemical imparting caramel color, 30 microgram in a can is carcinogenic, while it is found even up to 140 microgram  in a can of these soft drinks.
4. Food dyes, affecting human brain, focus impairment.
5. High fructose corn sirup, these are concentrated sugar. A can of soft drink contains 8 table spoons, which causes the increase in body fat and cholesterol including the Type-2 diabetes.
6. Formaldehyde, Soda contains espartem, which in digestion process break in to Methanol and then in to Formic Acid and Formaldehyde, which is carcinogenic. 
7. Potassium Benzoate, used as preservative, which turns in to Benzene in human body. Benzene is carcinogenic. Keeping soda in sun light, it turns in to Benzene.
Sugar is enemy, Dr. Parwez Ahmad, ex CEO of Max Healthcare says that all caffeine included sugar drinks-which provides instant energy, but affects our metabolism in adverse ways in longer terms and are responsible for chronic diseases. This can cause Obesity and Diabetes.
Soft drinks and health  
hazards/Dainik Bhaskar/
 14th April 2013, Sun
Soft Drinks causing 183 thousand death annually in the world, as per the researchers of 'Harvard School of Public Health.
# Out of which, 133 thousand died of diabetes, 44,000 due to cardiovascular diseases, and 6,000 died of cancer.
# 75% deaths were in lower income group of countries.
# Mexio has the highest rate of such deaths. Out of all the 1million deaths reported-318 deaths are linked to soft drink consumption.
# Japan having the lowest rate of such deaths. Out of all 1million deaths of adults, only 10 are linked to soft drink consumption.

A government report on soft drink addiction in India; Indian Council of Medical Research (ICMR) prepared a report on soft drink consumption in India, in 2011. This reports opens many facts about the addiction of carbonated drinks in India.
* 17.45% population of India drinks soft drink every week.
* Almost 18.47% children drink soft drink once in a week.
* 3.79% Indian population drinks cola everyday.
* Out of all the 18 years age children, 4.14% drinks cola every day.
* Contrary to the common beliefs, slum dwellers (23.90) drink more cola per week as compared to the  high income group (20.21).

Alarming increase in cola consumption; From 2009 to 2011, sale of Pepsi Cocacola have increased with a rate of 50% in India.

What happens to our body after drinking Coca Cola?
http://www.whydontyoutrythis.com/2013/09/what-happens-to-our-body-after-drinking-coca-cola.html
 


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#report thankfully shared from a report on soft drinks and health hazards/dainik bhaskar/bilaspur/14th April 2013, Sunday.

Tuesday, August 20, 2013

Prostate Specific Antigen: A misnomer and immune suppressor for itself

The prostate (from Greek προστάτης – prostates, literally "one who stands before", "protector", "guardian") is a compound tubuloalveolar exocrine gland of the male reproductive system in most mammals.The function of the prostate is to secrete a slightly alkaline fluid, milky or white in appearance, that usually constitutes 50–75% of the volume of the semen along with spermatozoa and seminal vesicle fluid. Semen is made alkaline overall with the secretions from the other contributing glands, including, at least, the seminal vesicle fluid. The alkalinity of semen helps neutralize the acidity of the vaginal tract, prolonging the lifespan of sperm. The alkalinization of semen is primarily accomplished through secretion from the seminal vesicles.
PSA is an acronym for “prostate specific antigen,” a protein made specifically by the prostate gland (gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene). The biological role of the prostate is to contribute fluids and proteins to semen at ejaculation. The other glands that contribute fluids and proteins to semen are the seminal vesicles. The prostate and seminal vesicles contract at ejaculation; the seminal vesicles contribute proteins that are extremely large, making semen thick, thus concentrating the sperm in the vagina, close to the cervix, the opening to the uterus. PSA is a specific type of protein, an enzyme, that is capable of breaking up the large seminal vesicle proteins, making them shorter and less viscous, allowing the sperm to swim free of the ejaculate, through the cervix into the uterus and fallopian tubes in search of an egg.

Prostate-specific antigen is a misnomer: it is an antigen but is not specific to the prostate. Although present in large amounts in prostatic tissue and semen, it has been detected in other body fluids and tissues.
(In women, PSA is found in female ejaculate at concentrations roughly equal to that found in male semen. Other than semen and female ejaculate, the greatest concentrations of PSA in biological fluids are detected in breast milk and amniotic fluid. Low concentrations of PSA have been identified in the urethral glands, endometrium, normal breast tissue and salivary gland tissue. PSA also is found in the serum of women with breast, lung, or uterine cancer and in some patients with renal cancer.)
Contradictory role of PSA as disease indicator: PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. PSA is not a unique indicator of prostate cancer, but may be detect also prostatitis or benign prostatic hyperplasia.

PSA is produced in the epithelial cells of the prostate, and can be demonstrated in biopsy samples or other histological specimens using immunohistochemistry. Disruption of this epithelium, for example in inflammation or benign prostatic hyperplasia, may lead to some diffusion of the antigen into the tissue around the epithelium, and is the cause of elevated blood levels of PSA in these conditions.
More significantly, PSA remains present in prostate cells after they become malignant. Prostate cancer cells generally have variable or weak staining for PSA, due to the disruption of their normal functioning. Thus, individual prostate cancer cells produce less PSA than healthy cells; the raised serum levels in prostate cancer patients is due to the greatly increased number of such cells, not their individual activity. 
Another self contradictory biological role prostate as immune suppressor for itself: for the proteins and fluids contributed by the prostate to ejaculated semen is to block negative responses to sperm by cells of the immune system in the vagina to protect the female reproductive organs from bacterial infection. Laboratory studies by Bedford Research scientists have shown that even very small amounts of semen added to cultures of immune cells causes them to die within 24 hours. It seems possible that this suppression of immune response to protect sperm has the unwanted side effect of making the prostate gland itself “immune suppressed” and thus less capable of protecting itself from infections and cancer. Some men suffer from low grade infections of the prostate for years, a condition known as “chronic prostatitis.” Other men may also have chronic prostatitis, but without symptoms. Some studies indicate that chronic, low-grade infections can eventually lead to cancer. 


#share courtesy:
*http://www.bedfordresearch.org
*wikipedia.org
*encyclopedia britanica, inc.